We are looking for volunteers willing to participate in a study regarding a possible new method for the control of malaria vectors. More than 300.000.000 cases and more than 1.000.000 millions deaths yearly, only in Africa. Those are the approximate malaria figures.

Current tools for malaria control include treatment of cases, presumptive treatment of apparently healthy individuals, prevention with bednets and insecticides. The appearance of resistant parasites and vectors threats to render all theses measures ineffective. Alternative and innovative methods are urgently needed to stop resistance spread and control the vectors.

Ivermectin is a drug that has been in use for the more than 25 years. It is an effective antihelminthic. It is also very effective for the control of onchocerciasis, in the context of the Onchocerciasis Control Programme in Africa more than 530 million doses have been safely administered to almost 70 million individuals.

After it is taken orally, ivermectin appears in the blood and slowly disappears in the next 12-14 days. It effectively kills most ectoparasites including scabies and louse. Some small experiments have shown that mosquitoes fed on a human who has taken ivermectin in the previous 14 days die more rapidly than those fed on a naïve individual.

We think ivermectin may have a role in the control of malaria. In order to investigate this possibility, we need to demonstrate its effects on mosquitoes comparing the survival of mosquitoes fed on treated individuals with the survival of those fed on untreated persons.

The experiment involves being randomly allocated to received the usual dose of ivermectin orally or nothing. Volunteers will be asked to place a cup containing 20 healthy, laboratory breed (NB free of disease)(...예, 예 뭐 그러시겠지요) mosquitoes to their forearm for 10 minutes on day one after the randomization and again on day 14.

Mosquitoes will be kept for 14 days and the survival on both groups will be then assessed and compared.

A compensation of 25 pounds(!!!!!!) will be given to every participant at the end of the study.

Experimentation will begin the first week of July 2008.

The study has been aproved by the school's ethics committee.


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학교 구인 광고 메일로는 이런게 날아오는 동네 입니다. 과연 기덕후들의 소굴답다. 어디 다른데는 인터뷰 한시간 해주면 20파운드 주던데 10분씩 2번 20마리의 모기에게 잔인하게 난도질 당하고 25파운드라니. 제법 훌륭하잖아. 돈에 미친 기덕후는 오늘도 임상실험에 자원합니다. 5만원은 어디 땅파면 나온답니까.


+)그건 그거고 ivermectin이 이나 벼룩에게 효과가 있는건 알았지만 사람에게 주입해 모기를 죽인다는 발상, 참 신선하지 않습니까. 인간을 움직이는 살충제로 삼는다, 아 머리 좋고 아이디어 번뜩이는 사람이 너무 많다.